The Archery Range

stynalane:

shadowphoenixrider:

botanyshitposts:

botanyshitposts:

so uhhhhhh i know this is a plant blog but realtalk lads im a little freaked out by that wild ass new organ discovered in our bodies according to a paper published literally yesterday am i right my lads, my bois, lmao hhaha

(as of 3/28/2018, paper was published in the reputable international research journal “Nature” on 3/27/2018, publication here, study was started in 2013) ok so like uhhh this is my rough translation of the paper they published using my current level of biological knowledge, if anyone else has a more in depth understanding with human anatomy things and would like to add on with anything i might have missed feel free to add but this is my takeaway: 

-scientists were looking at some stuff in the inside of a bile duct they were studying in a live patient (this will be important later) using a laser that lets them see the cells in real time. they injected some stuff into the duct and saw the spaces inbetween the cells fill up with fluid in strange, tube-like structures that didn’t correspond with what they expected to be there, so they sectioned and froze them to study them closer; they realized that upon closer inspection, the fluid-filled places were VERY small collagen tubes forming a complex matrix of bundles surrounded by a weird cell covering that seemed to connect them to one another. they called this the Interstitium. 

-they sectioned some more places where squeezy things might happen, like the inner linings of the bladder, lungs, lymph nodes, and the soft tissue enclosing our muscles, filled them with the same indicator, and hyper froze them like they did to the first sample and found the same weird matrix of fluid-filled tubing:

they concluded from what they found from this that: 

1. our previous thought of the space inbetween the cells in these parts of the body, which we thought were just kinda like, there or whatever doing nothing (a series of spaces that were already called the Interstitium that were largely ignored), are actually full of complex tubing running through a ton of very important parts of your body

2. when the structures they’re chilling around (like your bladder and bowel) contract, the fluid moves around all weird

3. the reason this wasn’t discovered before is because when the tubes are squished too hard- like when scientists are cutting into them- they have a tendency to collapse really easily, especially when being treated with chemicals for microscope use, giving the impression of the kind of tissues that we’ve traditionally seen in specimens and thought of being in these sensitive areas (closely compact and dense cell mats). it turns out that in living people, these tubes run between the cells carrying fluid; the scientists were able to see this initially in live patients using the above mentioned laser technology, and then took live biopsies by quickly freezing the cells in place before removal to prevent their collapse.

4. yes, these can move cancer cells around, which is HUGE seeing as they seem to enclose a LOT of important and delicate muscles in our bodies in one giant, complex system. when they looked at it in cancer patients, the tumors they found seemed to kind of be….leaking….into them…..because the tumors were putting pressure on the fluid tubes….which easily collapse…..and move things that fall into the fluid around….

5. the scientists also explored things like hernias and colon damage in relation to these, but unfortunately this is where my translation powers run out as non-plant-related terminology starts being used lmao im so sorry im like this

tl;dr: the membranes that surround some really important parts of squishy things like our stomach, bowels, colon, lungs, muscles, etc are full of very delicate and complex tubing that runs in a weirdly complex system to other important squishy things throughout our bodies and looks like a weird organ that we didn’t know was there before (or like, we knew about it, we just didn’t know it was so…connected and uh…organy). also it seems to have an impact on the spread of cancer throughout these regions

here’s the paper again if you want to have a read and see pics of the tubing itself and draw more in depth conclusions from it lmao 

Graduate of Biomedical Science here; this paper is pretty much understandable to me.

You’ve picked out the main stuff, but here’s some things I think is very interesting:

• The discovery of these spaces dramatically expands the lymphatic system. Basically, this is how the lymph nodes are connected to the rest of the body. Before it was kinda like ‘yeah here are the lymph nodes, and the lymph fluid kinda goes to the somehow? idk’. But now we have a whole system. It’s like discovering the entire circulatory system when before you only had the heart to work with.

• This is super important for cancers and detecting when a cancer has spread (metastasised, in the lingo). They talk about the spread of cancers into the deeper tissues (such as stomach cancers invading their submucosal tissue and skin cancers pentrating deeper into the dermis layers), but what is most important is that they detected the cancers spreading into the interstitial spaces before there was anything to detect within the lymph nodes. This is super important, as usually lymph node biopsies are done to detect if a cancer is spreading; this is before that very stage. This is literally catching cancers in the act of spreading before they’ve hit another organ this is fucking incredible.

• It’s providing an explanation for oedema (or edema, for my US followers), which is the build-up of fluid in certain areas of the body (usually the lower limbs, but it can be anywhere). For so long it’s been like ‘I guess there’s something wrong with your blood vessels??’ but like the lymphatic system, we’ve now got another explanation. ‘Ah, okay, there’s something going down in your interstitial fluid!’ A more effective diagnosis and treatment could be made, Bam! Enrich more people’s lives.

• They may play a role in how scar formation works. Some scar tissue can get a bit crazy and grow too much, meaning it needs to be cut away as it hinders movement or it just fucking painful. Perhaps the interstitial tubing/fluid plays a role in this, considering collagen is used in scar tissue, and these spaces are full of it.

• There’s clearly communication between these spaces and the digestive system, as they found tattoo pigment from the intestines in these spaces. Tattooing in the intestine is done to mark lesions for removal or observation later on, so the fact this pigment is actively moving out of the digestive system and else means it could play a role in disease we don’t know much about, like inflammatory bowel conditions.

Basically, THIS IS FUCKING HUGE AND COULD POTENTIALLY CHANGE THE GAME IN A BIG WAY.

Thank you OP for sharing this, I haven’t nerded out and been so fascinated by a study in a long time.

ALSO GOOD ON YOU NATURE FOR MAKING THE FULL ARTICLE FREE. HONOUR ON YOU AND YOUR COWS.

This feels like it’s going to be very important for us spoonies too.

jenroses:

properrussian:

thegayestpolyglot:

kingdeino:

useless-polandfacts:

useless-czechrepfacts:

wednesdaythunder:

geritashipper:

you-tit:

mikaisyuu:

natsui:

zhanaform:

somalang:

lingumaniac:

polyglottica:

perilegs:

tobdog:

sprachtraeume:

languageoclock:

af-hverju:

littlenerdygirlwithwings:

af-hverju:

me: why are you destroying earth!!!

aliens: because theres people who think that english is the only language they need to speak

me: thats fair i understand

For some reason I find this all the more amusing because it’s written in English

moi: pourquoi vous détruisez le monde!!!
l’extraterrestre: parce que il y a des gens qui pensent que l’anglais est le seule langue pour parler
moi: ah ça c’est bien

ich: warum zerstört ihr die erde!!!

aliens: weil es leute gibt die glauben dass englisch die einzige sprache ist die sie sprechen müssen

ich: das ist fair ich verstehe

ég: af hverju eyðileggið þið jörðina!!!
aliens: af því að það er fólk sem finnst að enska sé sú eina tungumál sem þau þurfa að tala
ég: oh, það er vit í þessu. ég skil.

ik: waarom vernietig je de aarde!!!

aliens: omdat er mensen zijn die denken dat engels de enige taal is die ze hoeven te spreken

ik: oh zo, ik snap het

minä: miks te tuhootte maapalloo?

alienit: koska tääl on ihmisiä joitten mielestä englanti on ainoo kieli jota niitten täytyy puhua

minä: toi on reilua, ymmärrän

私: どうして地球を滅ぼしているんですか？

宇宙人: 英語しか喋る必要がないと思う人がいるからです

私: なるほど、わかりました

me: Wosück maakt ji de Welt twei!!!

aliens: wieldat dat Lüüd gifft, de dinkt dat Engelsch de allenige Spraak weer, de een snacken mütt

me: jo, daar seggst wat. Nu versta ik’t

aniga: dhulka maxaad u burburinaya !!!

shisheeyaha: dadka intiisa badani u malaynayaan in Ingiriisidu tahay afka oo kaliya ay u baahan yihiin inay la hadlaan

aniga: waxaan fahamsanahay. waa wax cadaalad

我：你们为什么在毁灭地球?！！

外星人：因为有人以为他们只会英语就可以了

我：懂了，说得有道理

ako: bakit niyo sinisira ang mundo!!!

taga-ibang planeta: kasi merong mga taong akala nila Ingles lang ang kailangan nilang matutunang lenggwahe

ako: ah, sige naiintindihan ko

Aku : kenapa kau hancurkan bumi!!!
Alien : karena masih banyak orang berpikir hanya bahasa inggris satu-satunya bahasa yang terpenting
Aku : oh, oke lah..

tôi: tại sao các người hủy diệt trái đất!!!

người ngoài hành tinh: bởi vì có người nghĩ rằng tiếng Anh là thứ tiếng duy nhất mà họ cần biết

tôi: ồ thế thì tôi hiểu

Eu: Por que vocês estão destruindo a Terra?!
Aliens: Porque há pessoas que pensam que o inglês é a única língua que eles precisam falar.
Eu: Isso é justo, eu entendo.

jag: varför förintar ni jorden!!!

utomjordingar: för det finns folk som tror att engelska är det ända språket de behöver kunna

jag: rimligt, jag förstår

Já: Proč ničíte Zemi?

Mimozemšťani: Protože tu jsou lidé, kteří si myslí, že angličtina je jediný jazyk, který potřebují znát

Já: To je fér, to chápu.

ja: dlaczego niszczycie Ziemię?

kosmici: ponieważ są ludzie, którzy myślą, że angielski to jedyny język, którego potrzebuję

ja: rozumiem, w porządku

io: perchè state distruggendo la terra!!!

alieni: perchè ci sono delle persone che credono che l’inglese sia l’unica lingua di cui hanno bisogno

io: capisco, mi sembra giusto

Yo: porqué estás destruyendo la tierra!?!?

Extraterrestre: porque hay personas quienes creen que inglés es la única lengua que se tiene que hablar.

Yo: te entiendo, es justo.

Я: Почему вы уничтожаете Землю?!?!
Инопланетяне: Потому что есть люди, которые считают, что им нужно говорить только по-английски.
Я: А, ну понятно, тогда ладно!

A modern Rosetta stone.

heathergreyfeather:

iatethepomegranate:

ocdplayer:

serioussarcsm:

ocdplayer:

captainirrayditation:

ocdplayer:

i have an idea in my head where thor is just like. painfully incapable of being cissexist.

like some transphobic reporter asks him abt his sexuality and he’s “i have been attracted to many of your midgardian genders” and “what” and “my current paramor is genderqueer” “are they male or female” “they are neither of those two genders, that is what i have just said!” “oh well what were they born as“ “oh no, dear friend, u appear to be confusing genderqueer with genderfluid! the lady mystique assures me that these are two very different things, [extremely extended explanation]”

y/y

oh  my gosh yes

“but what are they biologically?”

“…they are human.”

oh my god

“But what is between their legs?!”

“That is not of your concern, but on a good  day, myself!”

IM SCREAMING

#thor’s the kind of guy who would hear that joke #you know #‘who wears the pants in your relationship?’ #‘well if we’re doing it the right way #neither of us’ #and he’d just BELLOW with laughter #because yes no pants for both of us #excellent (via tinpanali)

@thevoidbetweenmyears

teenagerposts:

caffeinated-possum:

boyjawz:

the-edgier-bears:

valeria2067:

A student discussing Romeo & Juliet: Like, can you even IMAGINE being forbidden to love someone? The one person you want to marry is the person you can’t have? And all because of other people’s hatred?

My not-straight self: Yeah, that would…. um… be really bad… really not good…

Except gay marriage is a law now soooooo I don’t know maybe this post is out of date but still

This is really shocking news, but…. A world exists outside of America…. Amazing, I know…. try not to take it all in at once, it can be a bit overwhelming….

and gay people are still being killed and attacked here so….

please stop forgetting your lgbt brothers and sisters in the middle east, some of whom can get the death penalty for being gay